Students in a junior- and senior-level Anatomy and Physiology course have the opportunity to correct missed exam questions (“regrade”) and earn up to half of the original points missed. The three objectives of this study were to determine if (a) performance on the regrade assignment was correlated with scores on subsequent exams, (b) completing regrades improved grades on the comprehensive final exam and overall course grade, and (c) there was an optimal number of regrades that led to better student performance.