A special topics course combining two relevant and contemporary themes (forensic DNA analysis and illicit drug detection) was developed to stimulate student enthusiasm and enhance understanding of forensic science. Building on the interest of popular television shows such as CSI and Breaking Bad, this course connects essential concepts in biochemistry, genetics, molecular biology, organic chemistry, and general chemistry with criminal justice studies to kindle student interest using the forensic science theme. Available to students in criminal justice or natural science majors, the forensic science theme is the focus as students participate in interdisciplinary activities and discussions while exploring fundamental principles used to solve crimes. Requiring critical-thinking and problem-solving skills, the collaboration of students of different academic focus leads to the debunking of myths surrounding both police and forensic scientists, while developing an awareness of how law enforcement and scientists work together in reality.