This directed case study engages students in an accessible discussion of cancer pathogenesis, prevention, and risk factors. Students are introduced to “William,” a middle-aged man worried about his cancer risk. William seeks out his family physician to address his concerns and to learn about ways to decrease his risk of developing cancer. Students learn about the pathogenesis of cancer, including how cancerous cells differ from normal cells, how cancer arises, and how it progresses. Students examine both controllable and uncontrollable risk factors for cancer development, with a focus on nutrition and the design of an anti-cancer menu for a week’s worth of meals. The case study is written for lower-division undergraduate students and is accessible for both science and non-science majors. It introduces fundamental biology concepts and builds a strong foundation for students to critically evaluate online sources, an invaluable skill.