This interrupted case study tells the story of a middle-aged female, “Josie,” who receives a diagnosis of congestive heart failure. In a conversation with her cardiologist, Josie asks questions about heart anatomy, blood circulation, and the valve issue that led to the development of her condition. Acting as her doctor, students provide explanations to Josie’s questions. The case is designed to thoroughly familiarize students with heart anatomy and how blood moves through the pulmonary and systemic circuits. It requires students to go beyond simple memorization of structures and pathways by having them draw connections between basic textbook information and a common disease. This case study was developed for students in a year-long anatomy and physiology course taught at a community college, but is also generally appropriate for first- or second-year university students, students in nursing or other professional programs, and high school students in honors or AP anatomy and physiology courses.