In this directed case study, students investigate a clinical scenario involving a patient’s bout with a rare autoimmune disease, Susac syndrome. The patient, “Suzy,” goes through a series of tests that lead to a misdiagnosis before her condition is correctly identified. The case was inspired by medical literature documenting evidence of Susac syndrome in patients misdiagnosed with multiple sclerosis (MS). Students explore symptoms, diagnostic tests, and treatments that are needed for the proper identification and management of Susac syndrome, which is clinically underdiagnosed due to symptoms that often mimic those of MS. This case was developed for neuroscience or anatomy and physiology courses and covers important concepts in clinical neuroscience. It is particularly suited for undergraduates interested in pursuing careers in science and healthcare. Overall, students will gain a breadth of knowledge including disease pathology and the visual system.