Tension pneumothorax is a condition that is associated with air in the pleural space. In this case study, tension pneumothorax is caused by a rupture in the pleura of the lung due to blunt force trauma. Students are presented with a patient scenario that entails a physical assessment, vital signs, blood labs, medical history, and a method of treatment. Students must correlate lab and diagnostic testing to the underlying pathology, interpret the data, and create a treatment plan that is appropriate for a tension pneumothorax in the acute stages and follow-up period. The case was written for use with a modified team-based learning format involving groups of four to five students, but it could also be completed as an individual project. It is targeted to premedical/allied health students and is appropriate for any respiratory course at the undergraduate or graduate level in a biomedical science program, nursing science program, or for health-related professional courses such as advanced physiology or advanced pathophysiology.