In this directed case study, students first watch a brief video and then read a short passage about the 1984 Bhopal, India, disaster in which a Union Carbide pesticide plant released 30 metric tons of poisonous gas throughout the city. Through a combination of small group work and classroom discussion, students work through a set of questions designed to help them apply their basic chemistry knowledge in order to understand the physical and biological significance of a tragedy in which almost 20,000 people died, and nearly 200,000 people were exposed to highly toxic methyl isocyanate (MIC) gas. The events in Bhopal revealed that expanding industrialization in developing countries without concurrent evolution in safety regulations could have catastrophic consequences. The case is suitable for general chemistry, non-majors chemistry and allied health (i.e., GOB; general, organic, and biological) chemistry courses or courses that have familiarized students with Lewis dot structures, resonance structures, formal charges, molar mass, unit conversion or dimensional analysis, specific gravity or density, and balancing reactions.