Teaching the anatomy of the muscle system to high school students can be challenging. Students often learn about muscle anatomy by memorizing information from textbooks or by observing plastic, inflexible models. Although these mediums help students learn about muscle placement, the mediums do not facilitate understanding regarding integration of the skeletal and muscular systems. The lab activity presented here was created to make learning about muscle origins, insertions, and movement an interactive experience in which students construct full-size muscle models out of plastic skeletons, nylon stockings, and various types of tape.