Many girls come to school with few out-of-school experiences that properly prepare them for science in the classroom; however, boys often play with science toys and tinker with mechanical devices. Furthermore, when compared to boys, girls might not receive equal treatment in the science classroom. This unequal treatment sends a clear message to girls that science is not for them. An after-school science club for girls is an intervention strategy that can help to begin to alleviate these problems. This article offers practical suggestions for implementing such a program for elementary girls in your school.