This article describes a modular middle school curriculum that integrates science, math, social studies, and language arts. An adventure story creates the context for student learning of the academic content, which is made relevant to students by including environmental health themes. Most children can relate curriculum concepts to environmental health problems because they have such a problem or know of someone who does. Common conditions include allergies and asthma; poisoning from food, water, or air; exposure to chemical hazards and carcinogens; nutritional disorders; and assorted infectious diseases (NIEHS).