American Indian/Alaska Native (AI/AN) populations are in the midst of a Type 2 diabetes epidemic. To address this crisis, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) began funding a national initiative titled "Diabetes Education in Tribal Schools (DETS) K-12 Curriculum Project.” The lesson plans are structured in the 5E learning cycle and instructional model--Engage, Explore, Explain, Elaborate, and Evaluate because it supports a constructivist teaching strategy and is based on how student learning occurs.