This issue of The Science Teacher (TST) marks our 12th consecutive annual issue devoted to the theme “Science for All.” In its infancy, this special issue focused exclusively on the important topic of teaching science in multicultural classrooms. While TST will continue to actively seek and publish articles on teaching and learning practices for multicultural classrooms, we also recognize that diversity comes in many flavors. Over these dozen years, the Science for All theme has evolved to now serve as an umbrella for articles about a wide range of issues surrounding the inclusion of all learners. This current issue of TST continues this tradition. Our goal must be for all students to achieve science literacy. Science is for all.