Invasive species, commonly known as “invasives,” are nonnative plants, animals, and microbes that completely take over and change an established ecosystem. The consequences of invasives’ spread are significant. In fact, many of the species that appear on the Endangered Species list are threatened by invasives. Therefore, the topic of invasive nonnative species can provide the focus for projects that engage students in authentic science investigations. Here the author describes how she launched her students into a study of invasives while supporting their local environment using the 5E Learning Cycle (engage, explore, explain, extend, evaluate).