The movement of hazardous chemicals found in high school science laboratories and chemical storerooms can be risky business due to the increased likelihood of an accidental spill, contamination, or other type of mishap. Prudent safety planning and practice need to be addressed in order to eliminate or minimize the potential for chemical incidents. Giving thought to the guidelines outlined in this article will help initiate the process of moving chemical inventories within and between school laboratories and storerooms.