For some school districts, the convenience, organization, curriculum scope, and sequence provided by science kits make them a tempting choice for incorporating hands-on, process- and inquiry-based science in the classroom. When teachers consider adopting whole curricular packages or individual kits, they should make sure the safety piece is in place. This article addresses the following questions that teachers should consider before investing in a kit: Are the activities safe? Are the activities age appropriate? Is personal protective equipment included? Are Material Safety Data Sheets provided? Can the activity be done safely in a science classroom or science laboratory?